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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRZ1
All Species:
9.09
Human Site:
Y2179
Identified Species:
22.22
UniProt:
P23471
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23471
NP_002842.2
2315
254587
Y2179
L
E
A
T
Q
D
D
Y
V
L
E
V
R
H
F
Chimpanzee
Pan troglodytes
XP_001144786
2315
254683
Y2179
L
E
A
T
Q
D
D
Y
V
L
E
V
R
H
F
Rhesus Macaque
Macaca mulatta
XP_001083149
2319
261044
F2171
L
M
R
K
N
L
X
F
R
T
L
S
X
K
L
Dog
Lupus familis
XP_539545
1926
210053
V1806
V
H
D
E
P
G
G
V
T
A
G
T
F
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q05909
1442
161224
P1322
K
W
P
N
P
D
A
P
I
S
S
T
F
E
L
Rat
Rattus norvegicus
Q62656
2316
255324
Y2180
L
E
A
T
Q
D
D
Y
V
L
E
V
R
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507441
1902
205873
D1782
C
P
K
W
P
N
P
D
S
P
I
S
K
T
F
Chicken
Gallus gallus
Q98936
1422
159748
P1302
K
W
P
N
P
D
A
P
I
S
S
T
F
E
L
Frog
Xenopus laevis
NP_001084180
2271
252519
Q2143
V
L
E
V
R
H
F
Q
C
P
K
W
P
N
P
Zebra Danio
Brachydanio rerio
A4IFW2
1909
213435
A1789
R
E
F
K
V
T
D
A
R
D
G
Q
S
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
55.7
53.6
N.A.
32.4
82.1
N.A.
53
32.7
52.2
23.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
64.9
62.3
N.A.
44.7
89.3
N.A.
62.5
45.6
66.6
39.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
6.6
100
N.A.
6.6
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
6.6
N.A.
13.3
100
N.A.
20
13.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
0
0
0
20
10
0
10
0
0
0
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% C
% Asp:
0
0
10
0
0
50
40
10
0
10
0
0
0
0
0
% D
% Glu:
0
40
10
10
0
0
0
0
0
0
30
0
0
20
0
% E
% Phe:
0
0
10
0
0
0
10
10
0
0
0
0
30
0
40
% F
% Gly:
0
0
0
0
0
10
10
0
0
0
20
0
0
0
0
% G
% His:
0
10
0
0
0
10
0
0
0
0
0
0
0
30
0
% H
% Ile:
0
0
0
0
0
0
0
0
20
0
10
0
0
0
0
% I
% Lys:
20
0
10
20
0
0
0
0
0
0
10
0
10
10
0
% K
% Leu:
40
10
0
0
0
10
0
0
0
30
10
0
0
0
30
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
20
10
10
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
20
0
40
0
10
20
0
20
0
0
10
0
10
% P
% Gln:
0
0
0
0
30
0
0
10
0
0
0
10
0
0
0
% Q
% Arg:
10
0
10
0
10
0
0
0
20
0
0
0
30
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
10
20
20
20
10
0
0
% S
% Thr:
0
0
0
30
0
10
0
0
10
10
0
30
0
10
10
% T
% Val:
20
0
0
10
10
0
0
10
30
0
0
30
0
0
0
% V
% Trp:
0
20
0
10
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _